On 18 December 2006 the Council of Ministers adopted a new EU regulatory framework for Registration, Evaluation and Authorisation of CHemicals (REACH). The aim of REACH is to ensure that health and environment (including animals) are protected from adverse effects due to dangerous chemical substances. Acquiring the necessary knowledge on the properties of substances will entail some animal testing. ( http://ecb.jrc.it/reach/ )
The stable labelled isotope should serve as internal standards, in that their physicochemical properties would approximate so closely those of their unlabelled counterparts that resolution of the two species would occur only in the final step of the assay, when labelled and unlabelled forms would be distinguished from one another on the basis of their difference in molecular weight.
ALSACHIM offers a wide array of stable isotope labeled compounds and our synthesis team can deliver your custom synthesis compound for REACH projects:
- Isotopically Labeled Reference Standards
- Controlled Drug Standards (DEA)
- Metabolites