Therapeutic Drug Monitoring
The quantification of drugs in a matrix (whole blood, plasma, urine, etc.) allows to guarantee an adapted dosage to each patient, in order to optimize their clinical benefits, while reducing their side effects. The exact measurement of these substances is therefore essential.
Alsachim strong expertise lies in its ability to produce labeled internal standard with stable isotopes to quantify the concentration of biological substances. Based on this added value, we develop internal standards for our reagent kits to deliver high quality compounds to ensure good bioanalysis results.
Based on MRM technology and the use of stable labeled internal standards, Alsachim develops TDM Clinical Mass Diagnostic Kits enabling the simultaneous quantification of different drugs, and thus optimizing the Therapeutic Drug Monitoring (TDM) of drugs in patients.
Ready-to-use reagent kits
Our kits are totally ready-to-use medical devices using LC-MS/MS method. To ensure a repeatability and time saving, we propose turnkey solutions with:
- all components required for the analysis; calibrators, quality controls, internal standards, solvents, consumables, etc.
- analytical method to allow the drugs quantification
As a supplier of CE-IVD products, we attach great importance to the monitoring of our products and the support to our customers. We ensure that our products and services comply with regulations to ensure validated use for our customers.
DOSIMMUNE™: immunosuppressants in whole blood
We developed a reagent kit to quantify immunosuppressant drugs (Cyclosporin A, Sirolimus, Tacrolimus, Everolimus) in whole blood using LC-MS/MS. DOSIMMUNE™ is a complete kit, CE marked, ready-to-use with all the components and accessories required to monitor immunosuppressants in patient whole blood.
To facilitate the analysis of several compounds, Alsachim developed "Starter sets" to provide you a range of products to facilitate your analyses.
The starter set is based on the basics compounds required to make these kind of analyses, including unlabeled and labeled internal standard.Ask for a STARTER KIT