[13C,2H3]-7-Hydroxymethotrexate

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  • Product number: C289
  • CAS number: 5939-37-7 unlabeled
  • Molecular formula: C20H22N8O6
  • Molecular weight: 474,45 g.mol-1
  • Min. purity: 95,00 %
  • Min. isotopic enrichment: 99% 13C, 98% 2H
  • Synonyms: 13C-2H3-7-OHMTX, (S)-2-(4-(((2,4-Diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid-13C-d3, 4-Amino-7-hydroxy-10-methylpteroylglutamic acid-13C-d3, 7-Hydroxyamethopterin-13C-d3
  • Solubility: refer to COA
  • Stability: ≥ 1 year
  • Shipping: 24/48h for products in stock
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Product Number: C289
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Description

7-Hydroxymethotrexate is intended for Pharmaceuticals applications. 7-Hydroxymethotrexate is a useful methotrexate metabolite. All information about [13C,2H3]-7-Hydroxymethotrexate is provided in the MSDS. We deliver compounds with high purity levels and a comprehensive Certificate of Analysis. Connect to your member account to consult the documents.

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References

  1. CNS penetration of methotrexate and its metabolite 7-hydroxymethotrexate in mice bearing orthotopic Group 3 medulloblastoma tumors and model-based simulations for children Drug Metabolism and Pharmacokinetics - Volume 48, February 2023 (available online 19 August 2022), 100471 [...]

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