[2H8]-Abemaciclib

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  • Product number: C6976
  • CAS number: 1231929-97-7 unlabeled
  • Molecular formula: C27H24D8F2N8
  • Molecular weight: 514,66 g.mol-1
  • Min. purity: 98,00 %
  • Min. isotopic enrichment: 98% 2H
  • Synonyms: Abemaciclib-D8, N-[5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine-D8, LY-2835219-D8
  • Solubility: refer to COA
  • Stability: ≥ 1 year
  • Shipping: 24/48h for products in stock
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Product Number: C6976
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Description

Abemaciclib is intended for Pharmaceuticals applications; it is a type of cancer growth blocker that targets the proteins cyclin dependant kinase 4 and 6 (CDK4 and CDK6) and a treatment for breast cancer. All information about [2H8]-Abemaciclib is provided in the MSDS. We deliver compounds with high purity levels and a comprehensive Certificate of Analysis. Connect to your member account to consult the documents.

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References

  1. Therapeutic drug monitoring in breast cancer therapy – LC-MS/MS method for quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, ribociclib, and major metabolites abemaciclib M20 and M2 in human serum. Journal of Pharmaceutical and Biomedical Analysis, Volume 225, 20 February 2023, 115211 [...]

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